概述

  • 产品名称Anti-ABCC11抗体
    参阅全部 ABCC11 一抗
  • 描述
    小鼠单克隆抗体to ABCC11
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human, Chimpanzee, Rhesus monkey
  • 免疫原

    Recombinant fragment: FVPIAVKGLT NSKSAVMRFK KFFLQESPVF YVQTLQDPSK ALVFEEATLS WQQTCPGIVN GALELERNGH ASEGMTRPRD ALGPEEEGNS LGPELHKINL, corresponding to amino acids 433-533 of Human ABCC11 (NP_115972) with tag.

  • 阳性对照
    • Recombinant tagged human ABCC11 fragment.

性能

应用

Our Abpromise guarantee covers the use of ab76727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 154 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性ABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.
    • 细胞定位Membrane; Multi-pass membrane protein.
    • 数据库链接
    • 别名
      • ABCC 11 antibody
      • ATP binding cassette protein C11 antibody
      • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
      • ATP binding cassette sub family C member 11 antibody
      • ATP binding cassette transporter MRP8 antibody
      • ATP binding cassette transporter sub family C member 11 antibody
      • EWWD antibody
      • MRP8 antibody
      • Multi resistance protein 8 antibody
      • Multidrug resistance associated protein 8 antibody
      • OTTHUMP00000164191 antibody
      • WW antibody
      see all

    Anti-ABCC11 antibody 图像

    • Anti-ABCC11 antibody (ab76727) at 1 µg/ml + Recombinant tagged human ABCC11 fragment at 0.1 µg

      Secondary
      Goat anti-mouse IgG (H&L)-HRP conjugate at 1/5000 dilution

      Predicted band size : 154 kDa
      Observed band size : 37 kDa (why is the actual band size different from the predicted?)

    Anti-ABCC11 antibody (ab76727)参考文献

    ab76727 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"