概述

性能

应用

Our Abpromise guarantee covers the use of ab91451 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use at an assay dependent concentration.

ab37371 - Rat polyclonal IgG, is suitable for use as an isotype control with this antibody. 

WB 1/20 - 1/50. Predicted molecular weight: 162 kDa.
IHC-Fr 1/20.
ICC 1/20 - 1/50.

Acetone fixed cytospin preparations.

靶标

  • 功能
    ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
  • 组织特异性
    Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
  • 序列相似性
    Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABCC10 antibody
    • ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
    • ATP binding cassette, subfamily C, member 10 antibody
    • ATP-binding cassette sub-family C member 10 antibody
    • EST182763 antibody
    • mFLJ00002 antibody
    • MRP7 antibody
    • MRP7_HUMAN antibody
    • Multidrug resistance associated protein 7 antibody
    • Multidrug resistance-associated protein 7 antibody
    • SIMRP7 antibody
    see all

图片

  • ab91451 at 1/20 dilution staining ABCC10 in ABCC10 transfected HEK cells by Immunocytochemistry.

文献

This product has been referenced in:
  • De Souza R  et al. Chemotherapy dosing schedule influences drug resistance development in ovarian cancer. Mol Cancer Ther 10:1289-99 (2011). WB ; Mouse . Read more (PubMed: 21551263) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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