The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Detects a band of approximately 83 kDa (predicted molecular weight: 83 kDa).Can be blocked with Human ABCB7 peptide (ab66358).
功能Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
疾病相关Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
序列相似性Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.
ATP binding cassette sub family B (MDR/TAP) member 7 antibody
ATP binding cassette sub family B member 7 antibody
ATP binding cassette sub family B member 7 mitochondrial antibody
ATP binding cassette transporter 7 antibody
ATP-binding cassette sub-family B member 7 antibody
ATP-binding cassette transporter 7 antibody
Multidrug resistance protein 7 antibody
P-glycoprotein 7 antibody
Anti-ABCB7 antibody 图像
Western blot - Anti-ABCB7 antibody (ab116606)
All lanes : Anti-ABCB7 antibody (ab116606) at 1 µg/ml
Lane 1 : Thymus (Rat) Tissue Lysate Lane 2 : Human spinal cord tissue lysate - total protein (ab29188) Lane 3 : Human kidney tissue lysate - total protein (ab30203) Lane 4 : Human liver tissue lysate - total protein (ab29889)
Lysates/proteins at 10 µg per lane.
Secondary Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution Developed using the ECL technique
Performed under reducing conditions.
Predicted band size : 83 kDa Observed band size : 83 kDa
Exposure time : 90 seconds
Anti-ABCB7 antibody (ab116606)参考文献
has not yet been referenced specifically in any publications.