概述

  • 产品名称Anti-ABCB7抗体
    参阅全部 ABCB7 一抗
  • 描述
    兔多克隆抗体to ABCB7
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Synthetic peptide derived from within residues 100 - 200 of Human ABCB7.

    (Peptide available as ab66358.)

  • 阳性对照
    • This antibody gave a positive signal in the following tissue lysates: Rat Thymus, Human Spinal Cord, Human Kidney, Human Liver.

性能

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应用

Our Abpromise guarantee covers the use of ab116606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 83 kDa (predicted molecular weight: 83 kDa).Can be blocked with Human ABCB7 peptide (ab66358).

靶标

  • 功能Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
  • 疾病相关Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
  • 序列相似性Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABC transporter 7 protein antibody
    • ABC7 antibody
    • Abcb7 antibody
    • ABCB7_HUMAN antibody
    • ASAT antibody
    • Atm1p antibody
    • ATP binding cassette 7 antibody
    • ATP binding cassette sub family B (MDR/TAP) member 7 antibody
    • ATP binding cassette sub family B member 7 antibody
    • ATP binding cassette sub family B member 7 mitochondrial antibody
    • ATP binding cassette transporter 7 antibody
    • ATP-binding cassette sub-family B member 7 antibody
    • ATP-binding cassette transporter 7 antibody
    • EST140535 antibody
    • MDR7 antibody
    • mitochondrial antibody
    • Multidrug resistance protein 7 antibody
    • P-glycoprotein 7 antibody
    • PGP7 antibody
    see all

Anti-ABCB7 antibody 图像

  • All lanes : Anti-ABCB7 antibody (ab116606) at 1 µg/ml

    Lane 1 : Thymus (Rat) Tissue Lysate
    Lane 2 : Human spinal cord tissue lysate - total protein (ab29188)
    Lane 3 : Human kidney tissue lysate - total protein (ab30203)
    Lane 4 : Human liver tissue lysate - total protein (ab29889)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 83 kDa
    Observed band size : 83 kDa


    Exposure time : 90 seconds

Anti-ABCB7 antibody (ab116606)参考文献

ab116606 has not yet been referenced specifically in any publications.

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