概述

  • 产品名称Anti-ABCB6抗体
    参阅全部 ABCB6 一抗
  • 描述
    兔多克隆抗体to ABCB6
  • 经测试应用适用于: ICC/IF, ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    RAMNTQENATRARAVD

    , corresponding to internal sequence amino acids 440-455 of Human ABCB6

  • 阳性对照
    • KB cells transfected with the ABCB6 protein.

性能

应用

Our Abpromise guarantee covers the use of ab47837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF
ELISA
WB
  • 应用说明ELISA: 1/40000 - 1/200000.
    IF (microscopy): Use at an assay dependent dilution.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
    • 组织特异性Widely expressed. Highest expression in heart and skeletal muscles.
    • 序列相似性Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
      Contains 1 ABC transmembrane type-1 domain.
      Contains 1 ABC transporter domain.
    • 发展阶段Highly expressed in fetal liver.
    • 细胞定位Mitochondrion outer membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ABC antibody
      • ABC transporter umat antibody
      • ABC14 antibody
      • Abcb6 antibody
      • ABCB6_HUMAN antibody
      • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
      • ATP-binding cassette half-transporter antibody
      • ATP-binding cassette sub-family B member 6 antibody
      • ATP-binding cassette sub-family B member 6, mitochondrial antibody
      • DUH3 antibody
      • LAN antibody
      • MCOPCB7 antibody
      • Mitochondrial ABC transporter 3 antibody
      • mitochondrial antibody
      • Mt ABC transporter 3 antibody
      • Mt-ABC transporter 3 antibody
      • MTABC3 antibody
      • P glycoprotein related protein antibody
      • P-glycoprotein-related protein antibody
      • PRP antibody
      • Ubiquitously expressed mammalian ABC half transporter antibody
      • Ubiquitously-expressed mammalian ABC half transporter antibody
      • UMAT antibody
      see all

    Anti-ABCB6 antibody 图像

    • All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilution

      Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
      Lane 2 : KB cell lysate without a vector insert


      Predicted band size : 93 kDa
      Observed band size : 104 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 79 kDa (possible truncated form).

    Anti-ABCB6 antibody (ab47837)参考文献

    ab47837 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"