概述

  • 产品名称
  • 描述
    兔多克隆抗体to ABCB10
  • 特异性
    ab74815 detects endogenous levels of total ABCB10 protein.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence of human ABCB10.

  • 阳性对照
    • Extracts from COLO cells.

性能

应用

Our Abpromise guarantee covers the use of ab74815 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.
ELISA 1/40000.

靶标

  • 功能
    May mediate critical mitochondrial transport functions related to heme biosynthesis.
  • 组织特异性
    Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
  • 序列相似性
    Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • 细胞定位
    Mitochondrion inner membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABC transporter 10 protein antibody
    • ABCB10 antibody
    • ABCB10 ATP binding cassette, sub family B (MDR/TAP), member 10 antibody
    • ABCBA_HUMAN antibody
    • ATP binding cassette sub family B member 10, mitochondrial antibody
    • ATP binding cassette transporter 10 antibody
    • ATP-binding cassette sub-family B member 10 antibody
    • ATP-binding cassette transporter 10 antibody
    • EST20237 antibody
    • M ABC2 antibody
    • M-ABC2 antibody
    • mitochondrial antibody
    • Mitochondrial ATP binding cassette 2 antibody
    • Mitochondrial ATP-binding cassette 2 antibody
    • MTABC2 antibody
    see all

图片

  • All lanes : Anti-ABCB10 antibody (ab74815) at 1/500 dilution

    Lane 1 : extracts from COLO cells
    Lane 2 : extracts from COLO cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 79 kDa
    Observed band size : 79 kDa
    Additional bands at : 116 kDa,60 kDa. We are unsure as to the identity of these extra bands.

实验方案

文献

ab74815 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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