概述

  • 产品名称Anti-ABCA2抗体
    参阅全部 ABCA2 一抗
  • 描述
    兔多克隆抗体to ABCA2
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide, corresponding to a region between residues 125 and 175 of Human ABCA2 (NP_001597.2).

  • 阳性对照
    • 293T whole cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab91571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
  • 应用说明IP: Use at 5-15 µg/mg of lysate.
    WB: 1/2000 - 1/10000. Predicted molecular weight: 270 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
    • 组织特异性Highy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
    • 序列相似性Belongs to the ABC transporter superfamily. ABCA family.
      Contains 2 ABC transporter domains.
    • 细胞定位Endosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ABC2 antibody
      • Abca2 antibody
      • ABCA2_HUMAN antibody
      • ATP binding cassette 2 antibody
      • ATP binding cassette sub family A member 2 antibody
      • ATP binding cassette transporter 2 antibody
      • ATP binding cassette, sub family A (ABC1), member 2 antibody
      • ATP binding cassette, sub family A, member 2 antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 2 antibody
      • ATP-binding cassette 2 antibody
      • ATP-binding cassette sub-family A member 2 antibody
      • ATP-binding cassette transporter 2 antibody
      see all

    Anti-ABCA2 antibody 图像

    • All lanes : Anti-ABCA2 antibody (ab91571) at 0.4 µg/ml

      Lane 1 : 293T whole cell lysate at 50 µg
      Lane 2 : 293T whole cell lysate at 15 µg
      Lane 3 : 293T whole cell lysate at 5 µg

      Developed using the ECL technique

      Predicted band size : 270 kDa


      Exposure time : 3 minutes
    • Detection of ABCA2 by Western Blot of Immunoprecipitate.
      ab91571, at 1 µg/ml, staining ABCA2 in 293T whole cell lysate immunoprecipitated using ab91571 at 10 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
      Detection: Chemiluminescence with exposure time of 3 minutes.

    Anti-ABCA2 antibody (ab91571)参考文献

    This product has been referenced in:
    • Alla V  et al. E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. Cell Cycle 11:3067-78 (2012). Read more (PubMed: 22871739) »

    See 1 Publication for this product

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