Staurosporine (DMSO solution),蛋白kinase抑制剂(ab146588)
Key features and details
- Protein kinase inhibitor
- CAS Number: 62996-74-1
- Purity: > 98%
- Supplied in DMSO (1mM)
- Form / State: Liquid
- Source: Synthetic
概述
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产品名称
Staurosporine (DMSO solution),蛋白kinase抑制剂 -
描述
蛋白kinase抑制剂 -
纯度
> 98% -
CAS编号
62996-74-1 -
化学结构
性能
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化学名称
[9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3,2,1-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one -
分子量
466.54 -
分子式
C28H26N4O3 -
PubChem识别号
44259 -
存放说明
Store at -20°C. Store In the Dark. Store under desiccating conditions. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
溶解度概述
Supplied in DMSO (1mM) -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C6NCc5c2c4n(c1ccccc12)[C@@]3(C)O[C@H](C[C@@H](NC)[C@H]3OC)n7c4c(c56)c8ccccc78 -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (5)
ab146588 被引用在 5 文献中.
- O'Callaghan P et al. Piezo1 activation attenuates thrombin-induced blebbing in breast cancer cells. J Cell Sci 135:N/A (2022). PubMed: 35274124
- Li J et al. A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage. NAR Genom Bioinform 4:lqac065 (2022). PubMed: 36110898
- Cox D et al. Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli. NPJ Syst Biol Appl 8:46 (2022). PubMed: 36443335
- Akande OE et al. DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination. Cell Rep 26:3323-3335.e4 (2019). PubMed: 30893604
- Lynch JM et al. Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle. PLoS One 13:e0206801 (2018). PubMed: 30395621