概述

  • 产品名称
    Anti-VAP1抗体[174-5]
    参阅全部 VAP1 一抗
  • 描述
    小鼠单克隆抗体[174-5] to VAP1
  • 经测试应用
    适用于: WB, IHC-Fr, Functional Studies, Flow Cyt, ICC/IFmore details
  • 种属反应性
    与反应: Rat, Human
  • 免疫原

    Purified vessels from human peripheral lymph nodes

  • 阳性对照
    • Human tonsil tissue.
  • 常规说明


    This antibody inhibits lymphocyte infiltration in liver allograft rejection in rats.

性能

应用

Our Abpromise guarantee covers the use of ab81718 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50. Predicted molecular weight: 85 kDa.
IHC-Fr 1/50.
Functional Studies Use at an assay dependent concentration.
Flow Cyt 1/50. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF Use at an assay dependent concentration.

靶标

  • 功能
    Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
  • 组织特异性
    Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis.
  • 序列相似性
    Belongs to the copper/topaquinone oxidase family.
  • 翻译后修饰
    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    N- and O-glycosylated.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amine oxidase, copper containing 3 (vascular adhesion protein 1) antibody
    • AOC3 antibody
    • AOC3_HUMAN antibody
    • Copper amine oxidase antibody
    • HPAO antibody
    • Membrane copper amine oxidase antibody
    • Membrane primary amine oxidase antibody
    • Semicarbazide sensitive amine oxidase antibody
    • Semicarbazide-sensitive amine oxidase antibody
    • SSAO antibody
    • VAP-1 antibody
    • Vascular adhesion protein 1 antibody
    • VP97 antibody
    see all

图片

  • ab81718 at 1/50 dilution staining VAP1 in human tonsil tissue section by Immunohistochemistry (frozen sections).

文献

This product has been referenced in:
  • Martelius T  et al. Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection. Am J Pathol 165:1993-2001 (2004). Read more (PubMed: 15579442) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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