Anti-Unrip抗体(ab102001)
Key features and details
- Rabbit polyclonal to Unrip
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Unrip抗体
参阅全部 Unrip 一抗 -
描述
兔多克隆抗体to Unrip -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant protein fragment, corresponding to a region within amino acids 25-289 of Human Unrip (AAH00162).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab102001于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
1/500 - 1/3000. Predicted molecular weight: 38 kDa.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 38 kDa. |
靶标
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功能
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus. STRAP may play a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein. -
序列相似性
Belongs to the WD repeat STRAP family.
Contains 7 WD repeats. -
细胞定位
Cytoplasm. Nucleus. Localized predominantly in the cytoplasm but also found in the nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 510201 Cow
- Entrez Gene: 11171 Human
- Entrez Gene: 20901 Mouse
- Entrez Gene: 297699 Rat
- Omim: 605986 Human
- SwissProt: Q5E959 Cow
- SwissProt: Q9Y3F4 Human
- SwissProt: Q9Z1Z2 Mouse
see all -
别名
- MAP activator with WD repeats antibody
- MAWD antibody
- PTWD antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab102001 被引用在 2 文献中.
- Sapaly D et al. The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases. Front Mol Biosci 7:55 (2020). PubMed: 32363199
- Pruksakorn D et al. Oncogenic roles of serine-threonine kinase receptor-associated protein (STRAP) in osteosarcoma. Cancer Chemother Pharmacol 82:1039-1047 (2018). PubMed: 30276452