Anti-Tcl1抗体[1-21] (ab91211)

概述

  • 产品名称
    Anti-Tcl1抗体[1-21]
    参阅全部 Tcl1 一抗
  • 描述
    小鼠单克隆抗体[1-21] to Tcl1
  • 经测试应用
    适用于: WB, IP, IHC-P, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Daudi cells

性能

应用

Our Abpromise guarantee covers the use of ab91211 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IP
IHC-P
Flow Cyt
  • 应用说明
    Flow Cyt: Use 0.5µg for 106 cells in 100µl volume.
    IHC-P: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 13 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
    • 组织特异性
      Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
    • 疾病相关
      Note=Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci.
    • 序列相似性
      Belongs to the TCL1 family.
    • 细胞定位
      Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Microsomal fraction.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Anti TCL1A antibody
      • Lymphoma/leukemia, T-cell antibody
      • Oncogene TCL-1 antibody
      • Oncogene TCL1 antibody
      • P14 TCL1 antibody
      • P14 TCL1 protein antibody
      • Protein p14 TCL1 antibody
      • T cell leukemia 1 antibody
      • T cell lymphoma 1 antibody
      • T cell lymphoma 1A antibody
      • T-cell leukemia/lymphoma 1A antibody
      • T-cell leukemia/lymphoma protein 1A antibody
      • TCL 1 protein antibody
      • TCL1 antibody
      • TCL1 oncogene antibody
      • TCL1 PEN antibody
      • Tcl1a antibody
      • TCL1A antibody antibody
      • TCL1A_HUMAN antibody
      see all

    图片

    • Staining of Daudi cells with ab91211 at 0.25 µg (blue histogram), or purified Mouse IgG2b, isotype control at 0.25 µg (green histogram), followed by treatment with Biotin anti-Mouse IgG and Phycoerythrin (PE) Streptavidin. Total viable cells were used for analysis.

    文献

    ab91211 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for contacting us regarding ab108978 and ab91211. I've attached the recommended Abcam IHC-P protocol and a troubleshooting guide for you. Here is a link to the protocol as well: http://www.abcam.com/index.html?pageconfig=resource&rid=11384 ...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册