Anti-4-1BBL抗体(ab64912)
Key features and details
- Rabbit polyclonal to 4-1BBL
- Suitable for: ELISA, WB, ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-4-1BBL抗体
参阅全部 4-1BBL 一抗 -
描述
兔多克隆抗体to 4-1BBL -
宿主
Rabbit -
经测试应用
适用于: ELISA, WB, ICC/IF, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Human 4-1BBL (internal sequence).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab64912于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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WB |
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 27 kDa).
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ICC/IF |
1/500 - 1/1000.
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IHC-P |
Use at an assay dependent concentration. PubMed: 25409517
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说明 |
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ELISA
Use at an assay dependent concentration. |
WB
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 27 kDa). |
ICC/IF
1/500 - 1/1000. |
IHC-P
Use at an assay dependent concentration. PubMed: 25409517 |
靶标
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功能
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. -
组织特异性
Expressed in brain, placenta, lung, skeletal muscle and kidney. -
序列相似性
Belongs to the tumor necrosis factor family. -
细胞定位
Membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 8744 Human
- Omim: 606182 Human
- SwissProt: P41273 Human
- Unigene: 1524 Human
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别名
- 4 1BB L antibody
- 4 1BB ligand antibody
- 4 1BBL antibody
see all
图片
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ab64912, at a 1/500 dilution, staining Human 4-1BBL in HeLa cells, by Immunofluorescence, with (+) or without (-) immunising peptide.
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All lanes : Anti-4-1BBL antibody (ab64912) at 1/500 dilution
Lane 1 : Extracts from HUVEC cells
Lane 2 : Extracts from HUVEC cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 27 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted?
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab64912 被引用在 4 文献中.
- Cui Z et al. CD47 blockade enhances therapeutic efficacy of cisplatin against lung carcinoma in a murine model. Exp Cell Res 405:112677 (2021). PubMed: 34111474
- Eirin A et al. Metabolic Syndrome Interferes with Packaging of Proteins within Porcine Mesenchymal Stem Cell-Derived Extracellular Vesicles. Stem Cells Transl Med 8:430-440 (2019). PubMed: 30707002
- Yoshimori M et al. CD137 expression is induced by Epstein-Barr virus infection through LMP1 in T or NK cells and mediates survival promoting signals. PLoS One 9:e112564 (2014). IHC-P . PubMed: 25409517
- Dumitriu IE et al. High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome. Circ Res 110:857-69 (2012). PubMed: 22282196