PE Anti-TLR6抗体[TLR6.127] (ab171564)
Key features and details
- PE Mouse monoclonal [TLR6.127] to TLR6
- Suitable for: IP, ICC/IF, Flow Cyt, Functional Studies
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
概述
-
产品名称
PE Anti-TLR6抗体[TLR6.127]
参阅全部 TLR6 一抗 -
描述
PE小鼠单克隆抗体[TLR6.127] to TLR6 -
宿主
Mouse -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: IP, ICC/IF, Flow Cyt, Functional Studiesmore details -
种属反应性
与反应: Human -
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. Store In the Dark. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
-
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
TLR6.127 -
同种型
IgG1 -
研究领域
相关产品
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab171564于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IP |
Use at an assay dependent concentration.
|
|
ICC/IF |
Use at an assay dependent concentration.
|
|
Flow Cyt |
Use at an assay dependent concentration.
ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
|
Functional Studies |
Use at an assay dependent concentration.
For neutralization of biological activity, in vitro dilutions have to be made according to the amounts of TLR6 to be inactivated. |
说明 |
---|
IP
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Functional Studies
Use at an assay dependent concentration. For neutralization of biological activity, in vitro dilutions have to be made according to the amounts of TLR6 to be inactivated. |
靶标
-
功能
Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. -
组织特异性
Detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. -
序列相似性
Belongs to the Toll-like receptor family.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 TIR domain. -
细胞定位
Cell membrane. Cytoplasmic vesicle > phagosome membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 10333 Human
- Omim: 605403 Human
- SwissProt: Q9Y2C9 Human
- Unigene: 575090 Human
-
别名
- CD286 antibody
- CD286 antigen antibody
- TLR 6 antibody
see all
实验方案
数据表及文件
-
Datasheet download
文献 (0)
ab171564 尚未被引用在任何文献中。