APC Anti-TCR alpha + TCR beta抗体[IP26] (ab99859)
Key features and details
- APC Mouse monoclonal [IP26] to TCR alpha + TCR beta
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
概述
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产品名称
APC Anti-TCR alpha + TCR beta抗体[IP26]
参阅全部 TCR alpha + TCR beta 一抗 -
描述
APC小鼠单克隆抗体[IP26] to TCR alpha + TCR beta -
宿主
Mouse -
偶联物
APC. Ex: 645nm, Em: 660nm -
特异性
Recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood. -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Human -
免疫原
Human TCR alpha + TCR beta
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阳性对照
- Human peripheral blood T cells
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常规说明
Short term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
The purified antibody is conjugated with Allophycocyanin (APC) under optimum conditions. No reconstitution is necessary.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.2% BSA, PBS -
Concentration information loading...
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纯度
Size exclusion -
纯化说明
The unconjugated antibody was purified by protein A (G) affinity chromatography (>95% by SDS-PAGE). After conjugation, the antibody was purified by size exclusion chromatography and adjusted for direct use. -
克隆
单克隆 -
克隆编号
IP26 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab99859于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
or 100 µl of whole blood. |
说明 |
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Flow Cyt
Use at an assay dependent concentration. or 100 µl of whole blood. |
靶标
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相关性
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. -
细胞定位
Type I membrane protein. -
数据库链接
- Entrez Gene: 6955 Human
- Entrez Gene: 6957 Human
- Omim: 186880 Human
- Omim: 186930 Human
- SwissProt: P01848 Human
- SwissProt: P04435 Human
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别名
- FLJ22602 antibody
- MGC117436 antibody
- MGC22624 antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab99859 被引用在 1 文献中.
- Kuttruff S et al. NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood 113:358-69 (2009). PubMed: 18922855