概述

  • 产品名称
    Anti-TANC1抗体
  • 描述
    兔多克隆抗体to TANC1
  • 经测试应用
    适用于: ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: LQEGLQSKGR PVSPQSRAGI GKSLREPVAQ PGLLLQPSKQ AQIVKTSQHL GSGQSAVRNG SMKVQISSQN PPPSPMPGRI AATP, corresponding to amino acids 1491-1574 of Human TANC1.

  • 阳性对照
    • Human cerebellum tissue

性能

应用

Our Abpromise guarantee covers the use of ab122358 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 1 - 4 µg/ml.

Recommend PFA Fixation and Triton X-100 treatment

IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    May be a scaffold component in the postsynaptic density.
  • 序列相似性
    Belongs to the TANC family.
    Contains 11 ANK repeats.
    Contains 3 TPR repeats.
  • 翻译后修饰
    Phosphorylated; probably by MINK1 and TNIK upon stimulation by RAP2A.
  • 细胞定位
    Cell junction > synapse > postsynaptic cell membrane > postsynaptic density.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ankyrin repeat and coiled-coil domain-containing protein 1 antibody
    • KIAA1728 antibody
    • Protein TANC1 antibody
    • Rolling pebbles homolog B antibody
    • ROLSB antibody
    • TANC antibody
    • Tanc1 antibody
    • TANC1_HUMAN antibody
    • Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1 antibody
    • Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1 antibody
    • Tetratricopeptide repeat antibody
    • TPR domain ankyrin repeat and coiled coil containing antibody
    see all

图片

  • Immunofluorescent staining of Human cell line U-2 OS shows positivity in nucleus but not nucleoli and cytoplasm. Recommended concentration of ab122358 1-4 µg/ml. Cells treated with PFA/Triton X-100.
  • ab122358, at 1/35 dilution, staining TANC1 in parffin-embedded Human cerebellum tissue by Immunohistochemistry.

文献

ab122358 has not yet been referenced specifically in any publications.

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