Anti-Spermidine synthase抗体(ab111884)
Key features and details
- Rabbit polyclonal to Spermidine synthase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Spermidine synthase抗体
参阅全部 Spermidine synthase 一抗 -
描述
兔多克隆抗体to Spermidine synthase -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment, corresponding to a region within amino acids 22-209 of Human Spermidine synthase (AAH00309).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab111884 is purified by antigen-affinity chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111884于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 34 kDa.
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IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. or Tris-EDTA buffer ( PH8.0).
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 34 kDa. |
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. or Tris-EDTA buffer ( PH8.0). |
靶标
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功能
Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine. -
通路
Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1. -
序列相似性
Belongs to the spermidine/spermine synthase family.
Contains 1 PABS (polyamine biosynthesis) domain. - Information by UniProt
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数据库链接
- Entrez Gene: 6723 Human
- Omim: 182891 Human
- SwissProt: P19623 Human
- Unigene: 76244 Human
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别名
- OTTHUMP00000002170 antibody
- PAPT antibody
- Putrescine aminopropyltransferase antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab111884 被引用在 2 文献中.
- Chen J et al. Supramolecular trap for catching polyamines in cells as an anti-tumor strategy. Nat Commun 10:3546 (2019). PubMed: 31391464
- Bistulfi G et al. The essential role of methylthioadenosine phosphorylase in prostate cancer. Oncotarget 7:14380-93 (2016). WB . PubMed: 26910893