Anti-STAU2抗体(ab101446)
Key features and details
- Rabbit polyclonal to STAU2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-STAU2抗体
参阅全部 STAU2 一抗 -
描述
兔多克隆抗体to STAU2 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant fragment, corresponding to a region within amino acids 263-477 of Human STAU2 isoform 2 (AAH08369).
-
阳性对照
- U87-MG whole cell lysate
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab101446于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 59 kDa.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 59 kDa. |
靶标
-
功能
RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body. -
序列相似性
Contains 4 DRBM (double-stranded RNA-binding) domains. -
结构域
The DRBM 3 domain appears to be the major RNA-binding determinant. This domain also mediates interaction with XPO5 and is required for XPO1/CRM1-independent nuclear export. -
细胞定位
Cytoplasm. Nucleus. Nucleus > nucleolus. Endoplasmic reticulum. Shuttles between the nucleolus, nucleus and the cytoplasm. Nuclear export of isoform 1 is independent of XPO1/CRM1 and requires the exportin XPO5. Nuclear export of isoform 2 and isoform 3 can occur by both XPO1/CRM1-dependent and XPO1/CRM1-independent pathways. Found in large cytoplasmic ribonucleoprotein (RNP) granules which are present in the actin rich regions of myelinating processes and associated with microtubules, polysomes and the endoplasmic reticulum. Also recruited to stress granules (SGs) upon inhibition of translation or oxidative stress. These structures are thought to harbor housekeeping mRNAs when translation is aborted. - Information by UniProt
-
数据库链接
- Entrez Gene: 100125233 Cow
- Entrez Gene: 27067 Human
- Entrez Gene: 29819 Mouse
- Entrez Gene: 171500 Rat
- Omim: 605920 Human
- SwissProt: Q9NUL3 Human
- SwissProt: Q8CJ67 Mouse
- SwissProt: Q68SB1 Rat
see all -
别名
- 39K2 antibody
- 39K3 antibody
- DKFZp781K0371 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab101446 尚未被引用在任何文献中。