Anti-SRXN1抗体(ab92298)
Key features and details
- Goat polyclonal to SRXN1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-SRXN1抗体
参阅全部 SRXN1 一抗 -
描述
山羊多克隆抗体to SRXN1 -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human colon and kidney lysates
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab92298 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab92298于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (4) |
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa).
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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相关性
SRXN1 contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. It does not act on PRDX5 or PRDX6. SRXN1 may catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. -
细胞定位
Cytoplasmic -
数据库链接
- Entrez Gene: 140809 Human
- Entrez Gene: 296271 Rat
- SwissProt: Q9BYN0 Human
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别名
- C20orf1392 antibody
- Chromosome 20 open reading frame 139 antibody
- dJ850E9.2 antibody
see all
图片
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Anti-SRXN1 antibody (ab92298) at 0.5 µg/ml + Human Kidney lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 14 kDa
Observed band size: 16 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour.
数据表及文件
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Datasheet download
文献 (3)
ab92298 被引用在 3 文献中.
- He J et al. Sulfiredoxin-1 attenuates injury and inflammation in acute pancreatitis through the ROS/ER stress/Cathepsin B axis. Cell Death Dis 12:626 (2021). PubMed: 34140464
- Barquilha CN et al. Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer. Oxid Med Cell Longev 2020:2148562 (2020). PubMed: 32411320
- Trstenjak Prebanda M et al. Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages. Cells 8:N/A (2019). PubMed: 31766320