Anti-SOX4抗体[154C4a] (ab70598)
Key features and details
- Mouse monoclonal [154C4a] to SOX4
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG2a
概述
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产品名称
Anti-SOX4抗体[154C4a]
参阅全部 SOX4 一抗 -
描述
小鼠单克隆抗体[154C4a] to SOX4 -
宿主
Mouse -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Recombinant fragment of human SOX4 from an internal sequence.
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阳性对照
- Recombinant human SOX4.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 0.1136% Dibasic monohydrogen sodium phosphate, 1% BSA, 0.03% Potassium phosphate, 0.812% Sodium chloride, 0.1312% Sodium phosphate, 0.0225% Potassium chloride, 0.0204% Monobasic dihydrogen potassium phosphate -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
ab70598 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum and filtered through a 0.22µm membrane. -
克隆
单克隆 -
克隆编号
154C4a -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab70598于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
Use at an assay dependent concentration. Detects a band of approximately 38 kDa (predicted molecular weight: 47 kDa).
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说明 |
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WB
Use at an assay dependent concentration. Detects a band of approximately 38 kDa (predicted molecular weight: 47 kDa). |
靶标
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功能
Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif. -
组织特异性
Testis, brain, and heart. -
序列相似性
Contains 1 HMG box DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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别名
- Ecotropic viral integration site 16 antibody
- EVI 16 antibody
- EVI16 antibody
see all
图片
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Anti-SOX4 antibody [154C4a] (ab70598) + immunising recombinant protein
Predicted band size: 47 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
The molecular weight of the band on the western blot does not correspond to the molecular weight of the natural protein because only a fragment of the protein was used.
数据表及文件
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Datasheet download
文献 (12)
ab70598 被引用在 12 文献中.
- Wu J et al. Circular RNA drives resistance to anti-PD-1 immunotherapy by regulating the miR-30a-5p/SOX4 axis in non-small cell lung cancer. Cancer Drug Resist 5:261-270 (2022). PubMed: 35800365
- Shen H et al. SOX4 promotes beige adipocyte-mediated adaptive thermogenesis by facilitating PRDM16-PPARγ complex. Theranostics 12:7699-7716 (2022). PubMed: 36451857
- Wu Y et al. LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis. Cancer Cell Int 21:284 (2021). PubMed: 34051810
- Xie J et al. HLA complex group 11 is involved in colorectal carcinoma cisplatin resistance via the miR-214-5p/SOX4 axis. Oncol Lett 22:535 (2021). PubMed: 34079592
- Wang L et al. A novel tumour suppressor protein encoded by circMAPK14 inhibits progression and metastasis of colorectal cancer by competitively binding to MKK6. Clin Transl Med 11:e613 (2021). PubMed: 34709743