Mouse, Rat, Guinea pig, Cow, Dog, Pig
A region within a synthetic peptide: QPPPEPFPAA SGSARAFREL PPLGAEFDGL GLPTPERSPL DGLEPGEAAF, corresponding to internal sequence amino acids 181-230 of Human SOX18
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Constituents: 2% Sucrose, PBS
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Use a concentration of 2 µg/ml. Detects a band of approximately 43 kDa (predicted molecular weight: 41 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.
Defects in SOX18 are the cause of hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) [MIM:607823].
Contains 1 HMG box DNA-binding domain.
Contains 1 Sox C-terminal domain.
Information by UniProt
SOX 18 antibody
Western blot - SOX18 antibody (ab23342)
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