Anti-ST3Gal I抗体(ab96129)
Key features and details
- Rabbit polyclonal to ST3Gal I
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ST3Gal I抗体 -
描述
兔多克隆抗体to ST3Gal I -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Cow -
免疫原
Recombinant fragment corresponding to Human ST3Gal I aa 1-165.
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阳性对照
- 293T, A431, H1299 Cell lysate. HeLaS3 whole cell lysate (WB). Sections of serous OVCA (IF).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96129于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
1/500 - 1/3000. Predicted molecular weight: 39 kDa.
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IHC-P |
1/100.
|
说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 39 kDa. |
IHC-P
1/100. |
靶标
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功能
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. -
组织特异性
Expressed in several tissues. Highest expression in lung, liver, skeletal muscle, kidney, pancreas, spleen and placenta. -
通路
Protein modification; protein glycosylation. -
序列相似性
Belongs to the glycosyltransferase 29 family. -
翻译后修饰
The soluble form derives from the membrane form by proteolytic processing. -
细胞定位
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. - Information by UniProt
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数据库链接
- Entrez Gene: 282351 Cow
- Entrez Gene: 6482 Human
- Omim: 607187 Human
- SwissProt: Q11201 Human
- Unigene: 374257 Human
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别名
- 3-GalNAc-alpha-2 antibody
- 3-sialyltransferase 1 antibody
- 3-sialyltransferase antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab96129 被引用在 3 文献中.
- Wen KC et al. a2,3-sialyltransferase type I regulates migration and peritoneal dissemination of ovarian cancer cells. Oncotarget 8:29013-29027 (2017). WB, IHC . PubMed: 28423672
- Li Y et al. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. Lab Invest 96:731-40 (2016). PubMed: 27088512
- Bai Q et al. Prognostic significance of ST3GAL-1 expression in patients with clear cell renal cell carcinoma. BMC Cancer 15:880 (2015). PubMed: 26552809