概述

  • 产品名称
  • 描述
    山羊多克隆抗体to SCAP2
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog
  • 免疫原

    Synthetic peptide:

    (C)GLVPKAYIMEMYDI

    , corresponding to C terminal amino acids 346-359 of Human SCAP2

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • 纯度
    Ammonium Sulphate Precipitation
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab2484 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    ELISA: 1/32000.
    WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 42.2 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway.
    • 组织特异性
      Ubiquitously expressed. Present in platelets (at protein level).
    • 序列相似性
      Belongs to the SKAP family.
      Contains 1 PH domain.
      Contains 1 SH3 domain.
    • 结构域
      The SH3 domain interacts with FYB and PTK2B.
    • 翻译后修饰
      Phosphorylated in resting platelets. Phosphorylated by FYN on Tyr-261 upon T-cell activation (Probable). Dephosphorylated on Tyr-75 by PTPN22.
    • 细胞定位
      Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Fyn associated phosphoprotein SKAP55 homologue antibody
      • MGC10411 antibody
      • MGC33 antibody
      • PRAP antibody
      • Pyk2/RAFTK associated protein antibody
      • Pyk2/RAFTK-associated protein antibody
      • RA70 antibody
      • Retinoic acid-induced protein 70 antibody
      • SAPS antibody
      • SKAP-55HOM antibody
      • SKAP-HOM antibody
      • skap2 antibody
      • SKAP2_HUMAN antibody
      • SKAP55 homolog antibody
      • SKAP55R antibody
      • Src associated adaptor protein antibody
      • Src family associated phosphoprotein 2 antibody
      • Src family-associated phosphoprotein 2 antibody
      • src kinase associated phosphoprotein of 55 related protein antibody
      • Src kinase-associated phosphoprotein 2 antibody
      • Src kinase-associated phosphoprotein 55-related protein antibody
      • Src-associated adapter protein with PH and SH3 domains antibody
      see all

    图片

    • Anti-SCAP2 antibody (ab2484) at 0.5 µg/ml + Jurkat lysate at 35 µg

      Predicted band size : 42.2 kDa

    实验方案

    文献

    This product has been referenced in:
    • Haanstra KG  et al. Expression patterns of regulatory T-cell markers in accepted and rejected nonhuman primate kidney allografts. Am J Transplant 7:2236-46 (2007). Read more (PubMed: 17845559) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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