SB 334867,OX1 receptor拮抗剂(ab120164)
Key features and details
- Selective OX1 receptor antagonist
- CAS Number: 792173-99-0
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
-
产品名称
SB 334867,OX1 receptor拮抗剂 -
描述
Selective OX1 receptor拮抗剂 -
生物学描述
Selective OX1 receptor antagonist. Inhibits orexin-A induced intracellular calcium release (IC50 = 226 nM). Shows anxiolytic, sedative and anorectic effects in vivo.
-
纯度
> 99% -
CAS编号
792173-99-0 -
化学结构
性能
-
化学名称
N-(2-Methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-ylurea -
分子量
319.32 -
分子式
C17H13N5O2 -
PubChem识别号
6604926 -
存放说明
Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in ethanol to 10 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES
CC1=NC2=C(O1)C=C(C=C2)NC(=O)NC3=C4C(=NC=C3)C=CC=N4 -
来源
Synthetic
-
研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (1)
ab120164 被引用在 1 文献中.
- Huang L et al. Low-intensity focused ultrasound attenuates early traumatic brain injury by OX-A/NF-κB/NLRP3 signaling pathway. Aging (Albany NY) 14:7455-7469 (2022). PubMed: 36126193