重组人Macrophage Inflammatory蛋白1 alpha / CCL3 (ab9674)
Key features and details
- Expression system: Escherichia coli
- Purity: > 99% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
-
产品名称
重组人Macrophage Inflammatory蛋白1 alpha / CCL3
参阅全部 MIP-1 alpha/CCL3 蛋白酶 -
纯度
> 99 % SDS-PAGE.
Sterile filtered Greater than 99% by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
预测分子量
10 kDa
-
-
描述
重组人MIP-1 alpha/CCL3蛋白
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab9674 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
Functional Studies
SDS-PAGE
-
形式
Lyophilized -
补充说明
The biological activity of this product is determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml. -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
-
复溶Please reconstitute this product in 200ul water.
常规信息
-
别名
- C C motif chemokine 3
- CCL 3
- CCL3
see all -
功能
Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
Datasheet download
文献 (1)
ab9674 被引用在 1 文献中.
- Jeong JH & Kang EB Effects of treadmill exercise on PI3K/AKT/GSK-3ß pathway and tau protein in high-fat diet-fed rats. J Exerc Nutrition Biochem 22:9-14 (2018). PubMed: 29673239