Recombinant人Tapasin protein (ab114877)

概述

  • 产品名称
    Recombinant人Tapasin protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      PGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEP WGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSL MPAT
    • 分子量
      37 kDa including tags
    • 氨基酸
      197 to 300

技术指标

Our Abpromise guarantee covers the use of ab114877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • NGS 17
    • NGS-17
    • NGS17
    • TAP associated protein
    • TAP binding protein
    • TAP binding protein (tapasin)
    • TAP BP
    • TAP-associated protein
    • TAP-binding protein
    • TAPA
    • Tapasin
    • TAPBP
    • TPN
    • TPSN
    • TPSN_HUMAN
    see all
  • 功能
    Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading).
  • 组织特异性
    Neutrophils, mostly in fully differentiated cells.
  • 序列相似性
    Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
  • 结构域
    The N-terminus is required for efficient association with MHC class I molecule and for a stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus region.
  • 细胞定位
    Endoplasmic reticulum membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE showing ab114877 at approximately 37.07kDa.
    Stained with Coomassie Blue.

文献

ab114877 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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