重组人KMT3C / SMYD2蛋白(ab107699)
Key features and details
- Expression system: Baculovirus infected Sf9 cells
- Purity: > 85% SDS-PAGE
- Suitable for: SDS-PAGE, WB
描述
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产品名称
重组人KMT3C / SMYD2蛋白
参阅全部 KMT3C / SMYD2 蛋白酶 -
纯度
> 85 % SDS-PAGE.
The purity was determined to be >85% by densitometry. Affinity purified. -
表达系统
Baculovirus infected Sf9 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
70 kDa including tags -
氨基酸
1 to 371
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技术指标
Our Abpromise guarantee covers the use of ab107699 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Western blot
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.50
Constituents: 0.307% Glutathione, 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 0.00292% EDTA, 25% Glycerol, 0.29% Sodium chloride
常规信息
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别名
- Histone methyltransferase SMYD2
- HSKM B
- HSKM-B
see all -
功能
Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates 'Lys-860' of RB1/RB. -
序列相似性
Contains 1 MYND-type zinc finger.
Contains 1 SET domain. -
细胞定位
Cytoplasm > cytosol. Nucleus. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab107699 尚未被引用在任何文献中。