重组人ERp57蛋白(ab92937)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: WB, SDS-PAGE
描述
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产品名称
重组人ERp57蛋白
参阅全部 ERp57 蛋白酶 -
纯度
> 95 % SDS-PAGE.
ab92937 is purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMSDV LELTDDNFES RISDTGSAGL MLVEFFAPWC GHCKRLAPEY EAAATRLKGI VPLAKVDCTA NTNTCNKYGV SGYPTLKIFR DGEEAGAYDG PRTADGIVSH LKKQAGPASV PLRTEEEFKK FISDKDASIV GFFDDSFSEA HSEFLKAASN LRDNYRFAHT NVESLVNEYD DNGEGIILFR PSHLTNKFED KTVAYTEQKM TSGKIKKFIQ ENIFGICPHM TEDNKDLIQG KDLLIAYYDV DYEKNAKGSN YWRNRVMMVA KKFLDAGHKL NFAVASRKTF SHELSDFGLE STAGEIPVVA IRTAKGEKFV MQEEFSRDGK ALERFLQDYF DGNLKRYLKS EPIPESNDGP VKVVVAENFD EIVNNENKDV LIEFYAPWCG HCKNLEPKYK ELGEKLSKDP NIVIAKMDAT ANDVPSPYEV RGFPTIYFSP ANKKLNPKKY EGGRELSDFI SYLQREATNP PVIQEEKPKK KKKAQEDL -
预测分子量
59 kDa -
氨基酸
25 to 505 -
标签
His tag N-Terminus -
额外的序列信息
Full length mature protein minus the signal peptide.
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab92937 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Western blot
SDS-PAGE
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形式
Liquid -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.0154% DTT, 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.58% Sodium chloride
常规信息
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别名
- 58 kDa glucose regulated protein
- 58 kDa glucose-regulated protein
- 58 kDa microsomal protein
see all -
组织特异性
Detected in the flagellum and head region of spermatozoa (at protein level). -
序列相似性
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains. -
细胞定位
Endoplasmic reticulum lumen. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab92937 被引用在 3 文献中.
- Hellewell AL et al. PDIA3/ERp57 promotes a matrix-rich secretome that stimulates fibroblast adhesion through CCN2. Am J Physiol Cell Physiol 322:C624-C644 (2022). PubMed: 35196163
- O'Sullivan ED et al. Single-cell analysis of senescent epithelia reveals targetable mechanisms promoting fibrosis. JCI Insight 7:N/A (2022). PubMed: 36509292
- Young HS et al. Impairment of cell adhesion and migration by inhibition of protein disulphide isomerases in three breast cancer cell lines. Biosci Rep 40:N/A (2020). PubMed: 33095243