重组人Annexin-2/ANXA2蛋白(ab93005)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.250 Eu/ml
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE, MS, WB, ELISA
描述
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产品名称
重组人Annexin-2/ANXA2蛋白
参阅全部 Annexin-2/ANXA2 蛋白酶 -
纯度
> 95 % SDS-PAGE.
Purified by 6xHis tag / Immobilized-metal affinity chromatography (IMAC). -
内毒素水平
< 0.250 Eu/ml -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
分子量信息
41.3 kDa -
标签
His tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab93005 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Mass Spectrometry
Western blot
ELISA
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形式
Liquid -
补充说明
This product was previously labelled as Annexin A2
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 7.4
Constituent: 100% PBS
常规信息
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别名
- Annexin A2
- Annexin II
- Annexin II, heavy chain
see all -
功能
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. -
序列相似性
Belongs to the annexin family.
Contains 4 annexin repeats. -
结构域
A pair of annexin repeats may form one binding site for calcium and phospholipid. -
翻译后修饰
Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
ISGylated. -
细胞定位
Secreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism. - Information by UniProt
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab93005 被引用在 4 文献中.
- Liu T et al. Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma. J Hematol Oncol 15:141 (2022). PubMed: 36209111
- Klabklai P et al. Annexin A2 Improves the Osteogenic Differentiation of Mesenchymal Stem Cells Exposed to High-Glucose Conditions through Lessening the Senescence. Int J Mol Sci 23:N/A (2022). PubMed: 36293376
- Ye Q et al. The important roles and molecular mechanisms of annexin A2 autoantibody in children with nephrotic syndrome. Ann Transl Med 9:1452 (2021). PubMed: 34734004
- Vais H et al. ER-luminal [Ca2+] regulation of InsP3 receptor gating mediated by an ER-luminal peripheral Ca2+-binding protein. Elife 9:N/A (2020). PubMed: 32420875