Anti-RDH5抗体(ab101457)
Key features and details
- Rabbit polyclonal to RDH5
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-RDH5抗体
参阅全部 RDH5 一抗 -
描述
兔多克隆抗体to RDH5 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Cow -
免疫原
Recombinant fragment corresponding to a region within amino acids 110-246 of Human RDH5 (AAH28298).
-
阳性对照
- NT2D1 whole cell lysate; A549, HeLa and Jurkat cell lysates; Cal27 xenograft
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab101457于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 35 kDa.
|
|
IHC-P |
1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Use 10mM Citrate buffer or Tris-EDTA buffer (pH8.0)
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 35 kDa. |
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Use 10mM Citrate buffer or Tris-EDTA buffer (pH8.0) |
靶标
-
相关性
RDH5 encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. -
细胞定位
Membrane; Peripheral membrane protein -
数据库链接
- Entrez Gene: 281448 Cow
- Entrez Gene: 5959 Human
- Entrez Gene: 19682 Mouse
- Omim: 601617 Human
- SwissProt: Q27979 Cow
- SwissProt: Q92781 Human
- SwissProt: O55240 Mouse
-
别名
- 11 cis RDH antibody
- 11 cis retinol dehydrogenase antibody
- 9 cis retinol specific dehydrogenase antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab101457 被引用在 2 文献中.
- Carlsson E et al. Increased Rate of Retinal Pigment Epithelial Cell Migration and Pro-Angiogenic Potential Ensuing From Reduced Cystatin C Expression. Invest Ophthalmol Vis Sci 61:9 (2020). PubMed: 32049341
- Samuel W et al. Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells. Mol Vis 23:60-89 (2017). Human . PubMed: 28356702