重组Anti-PTN抗体[EPR3041] (ab79411)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3041] to PTN
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
概述
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产品名称
Anti-PTN抗体[EPR3041]
参阅全部 PTN 一抗 -
描述
兔单克隆抗体[EPR3041] to PTN -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- WB: Human brain, Mouse brain, Mouse cerebellum, and Rat brain tissue lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR3041 -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab79411于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/1000. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
For unpurified use at 1/10000 - 1/20000. |
说明 |
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WB
1/1000. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa). For unpurified use at 1/10000 - 1/20000. |
靶标
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功能
Heparin binding mitogenic protein. Has neurite extension activity. -
组织特异性
Osteoblast and brain. -
序列相似性
Belongs to the pleiotrophin family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 5764 Human
- Entrez Gene: 19242 Mouse
- Entrez Gene: 24924 Rat
- Omim: 162095 Human
- SwissProt: P21246 Human
- SwissProt: P63089 Mouse
- SwissProt: P63090 Rat
- Unigene: 371249 Human
see all -
别名
- HARP antibody
- HB-GAM antibody
- HBBM antibody
see all
图片
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All lanes : Anti-PTN antibody [EPR3041] (ab79411) at 1/2000 dilution (Purified)
Lane 1 : Mouse brain lysate
Lane 2 : Mouse cerebellum lysate
Lane 3 : Rat brain lysate
Lysates/proteins at 20 µg per lane.
Secondary
All lanes : Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa -
Anti-PTN antibody [EPR3041] (ab79411) at 1/1000 dilution (Purified) + Human brain lysate at 15 µg
Secondary
Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab79411 被引用在 6 文献中.
- Jia B et al. CircRNA-PTN Sponges miR-326 to Promote Proliferation in Hepatocellular Carcinoma. Onco Targets Ther 13:4893-4903 (2020). PubMed: 32581550
- Huang P et al. Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-?B pathway in breast cancer cells. Cell Commun Signal 16:92 (2018). PubMed: 30497491
- Liu S et al. Knockdown of pleiotrophin increases the risk of preeclampsia following vitrified-thawed embryo transfer. Int J Oncol 53:1847-1856 (2018). PubMed: 30226583
- Zhu B et al. Array profiling reveals contribution of Cthrc1 to growth of the denervated rat urinary bladder. Am J Physiol Renal Physiol 314:F893-F905 (2018). PubMed: 29357417
- Kuboyama K et al. Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION. J Biol Chem 291:18117-28 (2016). PubMed: 27445335
- Kuboyama K et al. Inactivation of Protein Tyrosine Phosphatase Receptor Type Z by Pleiotrophin Promotes Remyelination through Activation of Differentiation of Oligodendrocyte Precursor Cells. J Neurosci 35:12162-71 (2015). PubMed: 26338327