Anti-Phosphoserine抗体[B106.1] (ab7851)
Key features and details
- Mouse monoclonal [B106.1] to Phosphoserine
- Suitable for: WB
- Reacts with: Species independent
- Isotype: IgG1
概述
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产品名称
Anti-Phosphoserine抗体[B106.1]
参阅全部 Phosphoserine 一抗 -
描述
小鼠单克隆抗体[B106.1] to Phosphoserine -
宿主
Mouse -
特异性
This antibody detects free and conjugated phosphoserine as well as phosphoserine in modified cellular proteins. It does not cross react with nonphosphorylated serine or with phosphotyrosine or phosphothreonine, neither does it cross react with AMP or ATP. However, due to steric hinderance, certain proteins known to contain phosphorylated serine may not be recognized by this antibody. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Species independent -
免疫原
Chemical/ Small Molecule corresponding to Phosphoserine conjugated to Keyhole Limpet Haemocyanin (KLH).
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阳性对照
- For immunoblotting we recommend extract of rat brain cortex.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
B106.1 -
同种型
IgG1 -
轻链类型
unknown -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
应用 | Ab评论 | 说明 |
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WB | (1) |
1/50.
Do not use milk as a blocking agent or in diluents, as milk casein is phosphorylated at several serine residues. BSA is recommended instead. |
说明 |
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WB
1/50. Do not use milk as a blocking agent or in diluents, as milk casein is phosphorylated at several serine residues. BSA is recommended instead. |
靶标
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相关性
Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated protein/peptides, antibodies against the phosphospecific amino acid, are important tools to explore the activation of serine, threonine or tyrosine containing proteins. An aberrant protein phosphorylation is a hallmark of human disease, and the enzymes, particularly protein kinases, which control protein phosphorylation are recognized as a major new drug target family. -
别名
- phospho-Ser antibody
- pS antibody
- pSER antibody
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab7851 被引用在 2 文献中.
- Wu Y et al. Activation of AMPKa2 in adipocytes is essential for nicotine-induced insulin resistance in vivo. Nat Med 21:373-82 (2015). WB, IP . PubMed: 25799226
- Gupta S et al. Kinase-actuated immunoaggregation of Peptide-conjugated gold nanoparticles. Small 6:1509-13 (2010). PubMed: 20578112