PE Anti-PD-L2抗体[TY25] (ab93589)
Key features and details
- PE Rat monoclonal [TY25] to PD-L2
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG2a
概述
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产品名称
PE Anti-PD-L2抗体[TY25]
参阅全部 PD-L2 一抗 -
描述
PE大鼠单克隆抗体[TY25] to PD-L2 -
宿主
Rat -
偶联物
PE. Ex: 488nm, Em: 575nm -
经测试应用
适用于: Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse PD-L2. Mouse PD-L2 transfected cell line.
Database link: Q9BQ51 -
阳性对照
- Flow Cyt: Mouse splenocyte suspensions and B7-DC-transfected cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
TY25 -
同种型
IgG2a -
轻链类型
kappa -
研究领域
相关产品
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Alternative Versions
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab93589于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
Flow Cyt |
Use 0.06-0.5µg for 105-8 cells.
|
说明 |
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Flow Cyt
Use 0.06-0.5µg for 105-8 cells. |
靶标
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功能
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. -
组织特异性
Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. -
序列相似性
Belongs to the immunoglobulin superfamily. BTN/MOG family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain. -
细胞定位
Secreted; Cell membrane and Endomembrane system. - Information by UniProt
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数据库链接
- Entrez Gene: 58205 Mouse
- SwissProt: Q9WUL5 Mouse
- Unigene: 116737 Mouse
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别名
- B7 dendritic cell molecule antibody
- B7-DC antibody
- B7DC antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (4)
ab93589 被引用在 4 文献中.
- Tanaka K et al. PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol 179:5204-10 (2007). PubMed: 17911605
- Kanai T et al. Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. J Immunol 171:4156-63 (2003). PubMed: 14530338
- Ansari MJ et al. The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 198:63-9 (2003). PubMed: 12847137
- Yamazaki T et al. Expression of programmed death 1 ligands by murine T cells and APC. J Immunol 169:5538-45 (2002). PubMed: 12421930