Anti-PANK1抗体(ab96173)
Key features and details
- Rabbit polyclonal to PANK1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-PANK1抗体
参阅全部 PANK1 一抗 -
描述
兔多克隆抗体to PANK1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Zebrafish -
免疫原
Recombinant fragment, corresponding to a region within amino acids 207-483 of Human PANK1.
-
阳性对照
- 293T, A431, H1299, HeLa S3, HepG2, Molt-4, Raji cells, NCIN87 xenograft
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96173于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 64 kDa.
|
|
IHC-P |
1/100 - 1/500.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 64 kDa. |
IHC-P
1/100 - 1/500. |
靶标
-
功能
Plays a role in the physiological regulation of the intracellular CoA concentration. -
组织特异性
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. -
通路
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. -
序列相似性
Belongs to the type II pantothenate kinase family. -
结构域
The N-terminal extension, present in isoform 1 may be the regulatory domain. -
细胞定位
Cytoplasm. - Information by UniProt
-
数据库链接
- Entrez Gene: 53354 Human
- Entrez Gene: 75735 Mouse
- Entrez Gene: 294088 Rat
- Omim: 606160 Human
- SwissProt: Q8TE04 Human
- SwissProt: Q8K4K6 Mouse
- Unigene: 376351 Human
- Unigene: 24742 Mouse
-
别名
- coaA antibody
- hPanK antibody
- hPanK1 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (2)
ab96173 被引用在 2 文献中.
- Zhang Y et al. Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E. Comput Math Methods Med 2021:6468405 (2021). PubMed: 34812269
- Machado MV et al. Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. Dig Dis Sci 61:137-48 (2016). PubMed: 26403427