Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee
Synthetic peptide corresponding to a region within internal sequence amino acids 288-337 (RRQLTKPRPV ILDPADPTGN LGGGDPKGWR QLAQEAEAWL NYPCFKNWDG) of human OAS1 (NP_001027581).
Transfected 293T cell lysate
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 2% Sucrose, PBS
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration.
Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.
Belongs to the 2-5A synthase family.
Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
Information by UniProt
(2 5')oligo(A) synthetase 1 antibody
(2-5'')oligo(A) synthase 1 antibody
2 5 Oligoadenylate Synthetase 1 antibody
Anti-OAS1 antibody (ab86343)参考文献
This product has been referenced in:
et al. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet 13:e1006820 (2017).
Read more (PubMed: 28640813) »
et al. p204-mediated innate antiviral responses in mouse adipose cells and their effects on cell functions. Immunol Cell Biol 93:147-57 (2015).
Read more (PubMed: 25287442) »
See all 6 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"