概述

  • 产品名称
  • 描述
    兔多克隆抗体to OAS1
  • 经测试应用
    适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 288-337 (RRQLTKPRPV ILDPADPTGN LGGGDPKGWR QLAQEAEAWL NYPCFKNWDG) of human OAS1 (NP_001027581).

  • 阳性对照
    • Transfected 293T cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab86343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.
  • 序列相似性
    Belongs to the 2-5A synthase family.
  • 细胞定位
    Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • (2 5')oligo(A) synthetase 1 antibody
    • (2-5'')oligo(A) synthase 1 antibody
    • 2 5 Oligoadenylate Synthetase 1 antibody
    • 2 5' oligo A synthase 1 antibody
    • 2 5' oligo A synthetase 1 antibody
    • 2 5A synthase 1 antibody
    • 2 5A synthetase 1 antibody
    • 2' 5' oligo A synthetase 1 antibody
    • 2' 5' oligoadenylate synthetase 1 40/46kDa antibody
    • 2' 5' oligoadenylate synthetase 1 antibody
    • 2' 5' oligoisoadenylate synthetase 1 antibody
    • 2''-5''-oligoadenylate synthase 1 antibody
    • 2'5' oligo A synthetase 1 antibody
    • 2'5' oligoadenylate synthetase 1 antibody
    • 2'5' oligoisoadenylate synthetase 1 antibody
    • 2-5A synthase 1 antibody
    • E18/E16 antibody
    • IFI 4 antibody
    • IFI4 antibody
    • OAS 1 antibody
    • OAS1 antibody
    • OAS1_HUMAN antibody
    • OIAS antibody
    • OIASI antibody
    • p46/p42 OAS antibody
    see all

图片

  • Anti-OAS1 antibody (ab86343) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 46 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small intestine tissue labelling OAS1 with ab86343.

文献

This product has been referenced in:
  • Li H  et al. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet 13:e1006820 (2017). WB ; Human . Read more (PubMed: 28640813) »
  • Yu L  et al. Functional Roles of Pattern Recognition Receptors That Recognize Virus Nucleic Acids in Human Adipose-Derived Mesenchymal Stem Cells. Biomed Res Int 2016:9872138 (2016). Read more (PubMed: 28105439) »

See all 7 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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