概述

  • 产品名称
  • 描述
    山羊多克隆抗体to NDUFS8
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Cow, Dog, Zebrafish
  • 免疫原

    Synthetic peptide:

    EAEIAANIQAD

    by a Cysteine residue linker, corresponding to internal sequence amino acids 196-206 of Human NDUFS8 (NP_002487.1.).

  • 阳性对照
    • Mouse heart lysate

性能

应用

Our Abpromise guarantee covers the use of ab106800 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 24 kDa.

靶标

  • 功能
    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone.
  • 疾病相关
    Defects in NDUFS8 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions.
  • 序列相似性
    Belongs to the complex I 23 kDa subunit family.
    Contains 2 4Fe-4S ferredoxin-type domains.
  • 细胞定位
    Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CI 23kD antibody
    • CI-23kD antibody
    • Complex I 23kD antibody
    • Complex I-23kD antibody
    • EC 1.6.5.3 antibody
    • EC 1.6.99.3 antibody
    • Human mitochondrial NADH dehydrogenase ubiquinone Fe S protein 8 antibody
    • NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial antibody
    • NADH ubiquinone oxidoreductase 23 kDa subunit antibody
    • NADH-ubiquinone oxidoreductase 23 kDa subunit antibody
    • NDUFS8 antibody
    • NDUS8_HUMAN antibody
    • TYKY antibody
    • TYKY subunit antibody
    • Ubiquinoneiron sulfur protein 8, mitochondrial precursor antibody
    see all

图片

  • Anti-NDUFS8 antibody (ab106800) at 0.1 µg/ml + Mouse heart lysate (RIPA buffer) at 35 µg/ml
    Developed using the ECL technique

    Predicted band size : 24 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)

实验方案

文献

ab106800 has not yet been referenced specifically in any publications.

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