FITC荧光Anti-Myeloperoxidase抗体[2D4] (ab90812)
Key features and details
- FITC Mouse monoclonal [2D4] to Myeloperoxidase
- Suitable for: Flow Cyt (Intra)
- Reacts with: Mouse, Rat
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG1
Related conjugates and formulations
概述
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产品名称
FITC荧光Anti-Myeloperoxidase抗体[2D4]
参阅全部 Myeloperoxidase 一抗 -
描述
FITC荧光小鼠单克隆抗体[2D4] to Myeloperoxidase -
宿主
Mouse -
偶联物
FITC. Ex: 493nm, Em: 528nm -
经测试应用
适用于: Flow Cyt (Intra)more details
不适用于: IHC-P or WB -
种属反应性
与反应: Mouse, Rat -
免疫原
Full length native protein (purified). This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Flow Cyt (Intra): Wehi3BD+ cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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纯化说明
ab90812 is 0.2 µm filtered -
克隆
单克隆 -
克隆编号
2D4 -
同种型
IgG1 -
研究领域
相关产品
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Alternative Versions
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Assay kits
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab90812于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Flow Cyt (Intra) |
1/50.
ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
说明 |
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Flow Cyt (Intra)
1/50. ab91356 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity. -
疾病相关
Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis. -
序列相似性
Belongs to the peroxidase family. XPO subfamily. -
细胞定位
Lysosome. - Information by UniProt
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数据库链接
- Entrez Gene: 17523 Mouse
- Entrez Gene: 303413 Rat
- SwissProt: P11247 Mouse
- Unigene: 4668 Mouse
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别名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (25)
ab90812 被引用在 25 文献中.
- Hawez A et al. c-Abl kinase regulates neutrophil extracellular trap formation and lung injury in abdominal sepsis. Lab Invest 102:263-271 (2022). PubMed: 34732849
- Huang S et al. Encountering and Wrestling: Neutrophils Recognize and Defensively Degrade Graphene Oxide. Adv Healthc Mater 11:e2102439 (2022). PubMed: 34859964
- Peng J et al. MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1G93A Motor Neuron of Amyotrophic Lateral Sclerosis. Oxid Med Cell Longev 2022:8217663 (2022). PubMed: 35178161
- Calabrese DR et al. NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes. JCI Insight 7:N/A (2022). PubMed: 36346670
- Wu X et al. TREM1 Regulates Neuroinflammatory Injury by Modulate Proinflammatory Subtype Transition of Microglia and Formation of Neutrophil Extracellular Traps via Interaction With SYK in Experimental Subarachnoid Hemorrhage. Front Immunol 12:766178 (2021). PubMed: 34721438