Anti-Muscarinic Acetylcholine Receptor M3/CHRM3抗体(ab60981)
Key features and details
- Rabbit polyclonal to Muscarinic Acetylcholine Receptor M3/CHRM3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Muscarinic Acetylcholine Receptor M3/CHRM3抗体
参阅全部 Muscarinic Acetylcholine Receptor M3/CHRM3 一抗 -
描述
兔多克隆抗体to Muscarinic Acetylcholine Receptor M3/CHRM3 -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Sheep, Horse, Hamster, Cow, Pig, Chimpanzee, Monkey, Gorilla, Common marmoset, Orangutan, Elephant -
免疫原
Synthetic peptide corresponding to Human Muscarinic Acetylcholine Receptor M3/CHRM3.
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阳性对照
- Heart tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab60981 was purified by peptide immunogen affinity column. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab60981于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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说明 |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
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功能
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily. -
细胞定位
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. Basolateral cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 469725 Chimpanzee
- Entrez Gene: 281685 Cow
- Entrez Gene: 101154508 Gorilla
- Entrez Gene: 1131 Human
- Entrez Gene: 100144478 Pig
- Omim: 118494 Human
- SwissProt: Q9N2A4 Chimpanzee
- SwissProt: P41984 Cow
see all -
别名
- AChR antibody
- ACM3_HUMAN antibody
- cholinergic receptor muscarinic 3 antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab60981 被引用在 1 文献中.
- Müller JJ et al. Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation. J Vasc Res 54:259-271 (2017). PubMed: 28810262