Anti-Mu Opioid Receptor抗体(ab17934)
Key features and details
- Rabbit polyclonal to Mu Opioid Receptor
- Suitable for: ICC, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-Mu Opioid Receptor抗体
参阅全部 Mu Opioid Receptor 一抗 -
描述
兔多克隆抗体to Mu Opioid Receptor -
宿主
Rabbit -
经测试应用
适用于: ICC, WBmore details -
种属反应性
与反应: Mouse, Rat
预测可用于: Human -
免疫原
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阳性对照
- WB: Rat brain lysates. ICC: Neuro-2A cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.05% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab17934于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ICC |
1/250.
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WB | (1) |
1/1000. Predicted molecular weight: 45 kDa.
|
说明 |
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ICC
1/250. |
WB
1/1000. Predicted molecular weight: 45 kDa. |
靶标
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功能
Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 4988 Human
- Entrez Gene: 18390 Mouse
- Entrez Gene: 25601 Rat
- Omim: 600018 Human
- SwissProt: P35372 Human
- SwissProt: P42866 Mouse
- SwissProt: P33535 Rat
- Unigene: 2353 Human
see all -
别名
- hMOP antibody
- LMOR antibody
- M-OR-1 antibody
see all
图片
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Anti-Mu Opioid Receptor antibody (ab17934) at 1/1000 dilution + Rat brain lysates
Secondary
Goat anti-rabbit IgG HRP conjugate.
Predicted band size: 45 kDaSDS-PAGE on a 10% Tris-glycine gel
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Neuro-2A cells stained for Mu Opioid Receptor (green) using ab17934 at 1/250 dilution in ICC/IF. It was followed by Goat anti-Rabbit IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate at 1/2000 dilution for 45 minutes at room temperature (Panel a). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI. F-actin (Panel c: red) was stained with Rhodamine Phalloidin at 1/300 dilution. Panel d represents the merged image showing membranous localization. Panel e shows the no primary antibody control.
数据表及文件
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SDS download
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Datasheet download
文献 (7)
ab17934 被引用在 7 文献中.
- Zhang JJ et al. Inhibition of mu-opioid receptor suppresses proliferation of hepatocellular carcinoma cells via CD147-p53-MAPK cascade signaling pathway. Am J Transl Res 13:3967-3986 (2021). PubMed: 34149993
- Blackwood CA et al. Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration. Mol Neurobiol 56:3603-3615 (2019). PubMed: 30155791
- Seoane-Collazo P et al. Central nicotine induces browning through hypothalamic ? opioid receptor. Nat Commun 10:4037 (2019). PubMed: 31492869
- Blackwood CA et al. Escalated Oxycodone Self-Administration and Punishment: Differential Expression of Opioid Receptors and Immediate Early Genes in the Rat Dorsal Striatum and Prefrontal Cortex. Front Neurosci 13:1392 (2019). PubMed: 31998063
- Hubbs AF et al. Accumulation of Ubiquitin and Sequestosome-1 Implicate Protein Damage in Diacetyl-Induced Cytotoxicity. Am J Pathol N/A:N/A (2016). ICC/IF ; Mouse . PubMed: 27643531
- Leoncikas V et al. Generation of 2,000 breast cancer metabolic landscapes reveals a poor prognosis group with active serotonin production. Sci Rep 6:19771 (2016). PubMed: 26813959
- Niwa H et al. Evaluation of primary opioid receptor antibodies for use in western blotting. Br J Anaesth 108:530-2 (2012). WB ; Rat . PubMed: 22337965