Anti-CXCL9抗体(ab9720)
Key features and details
- Rabbit polyclonal to CXCL9
- Suitable for: ELISA, Sandwich ELISA, Neutralising, WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-CXCL9抗体
参阅全部 CXCL9 一抗 -
描述
兔多克隆抗体to CXCL9 -
宿主
Rabbit -
经测试应用
适用于: ELISA, Sandwich ELISA, Neutralising, WB, IHC-Pmore details -
种属反应性
与反应: Human -
免疫原
Recombinant full length protein corresponding to Human CXCL9. Highly pure (>98%) recombinant hMIG (human Monokine induced by Interferon-Gamma)
Database link: Q07325 -
阳性对照
- WB: Recombinant human CXCL9 protein (ab9721).
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常规说明
Although some customers have been successful in IHC we no longer batch test in this application.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute with 200µl of sterile water. -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
No preservative, sterile filtered -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
轻链类型
unknown -
研究领域
相关产品
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Compatible Secondaries
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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Sandwich ELISA |
Use a concentration of 0.5 - 2 µg/ml.
To detect hOPG by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with suitable detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hOPG. |
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Neutralising |
Use at an assay dependent concentration.
To yield one-half maximal inhibition [ND50] of the biological activity of hMIG (100.00 ng/ml), a concentration of 5.0 - 7.0 µg/ml of this antibody is required |
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WB |
Use at an assay dependent concentration.
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IHC-P | (2) |
Use at an assay dependent concentration.
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说明 |
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ELISA
Use at an assay dependent concentration. |
Sandwich ELISA
Use a concentration of 0.5 - 2 µg/ml. To detect hOPG by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with suitable detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hOPG. |
Neutralising
Use at an assay dependent concentration. To yield one-half maximal inhibition [ND50] of the biological activity of hMIG (100.00 ng/ml), a concentration of 5.0 - 7.0 µg/ml of this antibody is required |
WB
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
靶标
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功能
Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. -
序列相似性
Belongs to the intercrine alpha (chemokine CxC) family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 4283 Human
- Omim: 601704 Human
- SwissProt: Q07325 Human
- Unigene: 77367 Human
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别名
- C-X-C motif chemokine 9 antibody
- chemokine (C-X-C motif) ligand 9 antibody
- CMK antibody
see all
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (10)
ab9720 被引用在 10 文献中.
- Choi YW et al. Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer. Adv Sci (Weinh) 8:2002497 (2021). PubMed: 33643790
- Zhang K et al. A ceRNA network and a potential regulatory axis in gastric cancer with different degrees of immune cell infiltration. Cancer Sci 111:4041-4050 (2020). PubMed: 32860283
- Meng Z et al. Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma. Aging (Albany NY) 12:5048-5070 (2020). PubMed: 32181755
- Meng Q & Qiu B Exosomal MicroRNA-320a Derived From Mesenchymal Stem Cells Regulates Rheumatoid Arthritis Fibroblast-Like Synoviocyte Activation by Suppressing CXCL9 Expression. Front Physiol 11:441 (2020). PubMed: 32528301
- Yue Y et al. Identification of key genes involved in JAK/STAT pathway in colorectal cancer. Mol Immunol 128:287-297 (2020). PubMed: 33248399
- Li H et al. Disparate roles of CXCR3A and CXCR3B in regulating progressive properties of colorectal cancer cells. Mol Carcinog 58:171-184 (2019). PubMed: 30302818
- Dangaj D et al. Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors. Cancer Cell 35:885-900.e10 (2019). PubMed: 31185212
- Liu W et al. Elevated expression of IFN-inducible CXCR3 ligands predicts poor prognosis in patients with non-metastatic clear-cell renal cell carcinoma. Oncotarget 7:13976-83 (2016). IHC . PubMed: 26910919
- Chmielewski S et al. STAT1-dependent signal integration between IFN? and TLR4 in vascular cells reflect pro-atherogenic responses in human atherosclerosis. PLoS One 9:e113318 (2014). IHC-P ; Human . PubMed: 25478796
- Xu J et al. Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis. Clin Infect Dis 41:1089-96 (2005). PubMed: 16163626