Anti-MIA2抗体(ab58973)
Key features and details
- Rabbit polyclonal to MIA2
- Suitable for: Sandwich ELISA, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MIA2抗体 -
描述
兔多克隆抗体to MIA2 -
宿主
Rabbit -
经测试应用
适用于: Sandwich ELISA, WBmore details -
种属反应性
与反应: Human -
免疫原
Highly pure (>98%) recombinant MIA2 (human).
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阳性对照
- WB: Recombinant Human MIA2.
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常规说明
Although some customers have been successful in IHC we no longer batch test in this application.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Lyophilized:Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab58973于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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Sandwich ELISA |
Use a concentration of 0.5 - 2 µg/ml.
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WB |
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 62 kDa.
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说明 |
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Sandwich ELISA
Use a concentration of 0.5 - 2 µg/ml. |
WB
Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 62 kDa. |
靶标
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功能
May play a role in the pathophysiology of liver disease and may serve as a marker of liver damage. -
组织特异性
Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. -
序列相似性
Belongs to the MIA/OTOR family.
Contains 1 SH3 domain. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 117153 Human
- Omim: 608001 Human
- SwissProt: Q96PC5 Human
- Unigene: 287694 Human
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别名
- FLJ22404 antibody
- Melanoma inhibitory activity 2 antibody
- Melanoma inhibitory activity protein 2 antibody
see all
数据表及文件
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Datasheet download
文献 (3)
ab58973 被引用在 3 文献中.
- Hei R et al. CircNRIP1 acts as a sponge of miR-1200 to suppress osteosarcoma progression via upregulation of MIA2. Am J Cancer Res 12:2833-2849 (2022). PubMed: 35812061
- Kurihara-Shimomura M et al. Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma. Int J Oncol 56:1093-1100 (2020). PubMed: 32319583
- Xu Y et al. The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene. Biochem Biophys Res Commun 416:379-84 (2011). Sandwich ELISA . PubMed: 22120627