Anti-MCP1抗体(ab25124)
Key features and details
- Rabbit polyclonal to MCP1
- Suitable for: WB, Neutralising, IHC-P, Flow Cyt
- Reacts with: Mouse, Rat
- Isotype: IgG
概述
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产品名称
Anti-MCP1抗体
参阅全部 MCP1 一抗 -
描述
兔多克隆抗体to MCP1 -
宿主
Rabbit -
特异性
ab25124 reacts with both rat MCP1 and its mouse homolog JE. -
经测试应用
适用于: WB, Neutralising, IHC-P, Flow Cytmore details -
种属反应性
与反应: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Rat MCP1 aa 1-73 (N terminal).
Sequence:MQVSVTLLGL LFTVAACSIH VLSQPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP KEAVVFVTKL KRE
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituent: 99.95% PBS -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Related Products
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab25124于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB | (2) |
Use at an assay dependent concentration.
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Neutralising |
Use at an assay dependent concentration.
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|
IHC-P | (2) |
Use at an assay dependent concentration.
|
Flow Cyt | (1) |
Use at an assay dependent concentration.
Used at a dilution of 1/100 for 30 min on rat primary mixed cortical cells (see Abreview for further information). ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
说明 |
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WB
Use at an assay dependent concentration. |
Neutralising
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. Used at a dilution of 1/100 for 30 min on rat primary mixed cortical cells (see Abreview for further information). ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody. |
靶标
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功能
Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. -
序列相似性
Belongs to the intercrine beta (chemokine CC) family. -
翻译后修饰
Processing at the N-terminus can regulate receptor and target cell selectivity. Deletion of the N-terminal residue converts it from an activator of basophil to an eosinophil chemoattractant. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 20296 Mouse
- Entrez Gene: 24770 Rat
- SwissProt: P10148 Mouse
- SwissProt: P14844 Rat
- Unigene: 290320 Mouse
- Unigene: 4772 Rat
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别名
- C-C motif chemokine 2 antibody
- CCL2 antibody
- CCL2_HUMAN antibody
see all
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (147)
ab25124 被引用在 147 文献中.
- Cao H et al. Effects of rAmb a 1-Loaded PLGA-PEG Nanoparticles in a Murine Model of Allergic Conjunctivitis. Molecules 27:N/A (2022). PubMed: 35163859
- Shi X et al. Cellular distribution of C-C motif chemokine ligand 2 like immunoreactivities in frontal cortex and corpus callosum of normal and lipopolysaccharide treated animal. BMC Neurosci 23:20 (2022). PubMed: 35354428
- Mizokami T et al. Macrophage Depletion Attenuates Acute Renal Damage after Exhaustive Exercise in Mice. Int J Sports Med 43:964-970 (2022). PubMed: 35426091
- Yin G et al. Upregulated lncARAT in Schwann cells promotes axonal regeneration by recruiting and activating proregenerative macrophages. Mol Med 28:76 (2022). PubMed: 35768768
- Yamasaki T et al. Inhibition of microRNA-33b specifically ameliorates abdominal aortic aneurysm formation via suppression of inflammatory pathways. Sci Rep 12:11984 (2022). PubMed: 35835906