Anti-MC2-R抗体(ab135908)
Key features and details
- Rabbit polyclonal to MC2-R
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-MC2-R抗体
参阅全部 MC2-R 一抗 -
描述
兔多克隆抗体to MC2-R -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
Synthetic peptide corresponding to Human MC2-R (C terminal).
-
阳性对照
- COLO205 cell lysates
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20ºC. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49.1% PBS, 0.88% Sodium chloride
PBS without Mg2+ or Ca2+ -
Concentration information loading...
-
纯度
Immunogen affinity purified -
纯化说明
The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab135908于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 34 kDa.
|
说明 |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 34 kDa. |
靶标
-
功能
Receptor for ACTH. This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase. -
组织特异性
Melanocytes and corticoadrenal tissue. -
疾病相关
Defects in MC2R are the cause of glucocorticoid deficiency type 1 (GCCD1) [MIM:202200]; also known as familial glucocorticoid deficiency type 1 (FGD1). GCCD1 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 4158 Human
- Entrez Gene: 17200 Mouse
- Omim: 607397 Human
- SwissProt: Q01718 Human
- SwissProt: Q64326 Mouse
- Unigene: 248144 Human
- Unigene: 426053 Mouse
-
别名
- ACTH receptor antibody
- ACTH-R antibody
- ACTHR antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab135908 尚未被引用在任何文献中。