Anti-Liver Arginase抗体(ab92274)
Key features and details
- Goat polyclonal to Liver Arginase
- Suitable for: WB
- Reacts with: Mouse, Rat, Human, Pig
- Isotype: IgG
概述
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产品名称
Anti-Liver Arginase抗体
参阅全部 Liver Arginase 一抗 -
描述
山羊多克隆抗体to Liver Arginase -
宿主
Goat -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse, Rat, Human, Pig
预测可用于: Rabbit, Cow, Dog -
免疫原
Synthetic peptide:
CFGLAREGNHKPID
, corresponding to C terminal amino acids 303-316 of Human liver Arginase (NP_000036.2). -
阳性对照
- WB: Pig, mouse, human and rat liver lysate.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Assay kits
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab92274于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa).
1 hour primary incubation is recommended for this product. |
说明 |
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WB
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa). 1 hour primary incubation is recommended for this product. |
靶标
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通路
Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. -
疾病相关
Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia. -
序列相似性
Belongs to the arginase family. -
细胞定位
Cytoplasm. - Information by UniProt
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数据库链接
- Entrez Gene: 383 Human
- Entrez Gene: 11846 Mouse
- Entrez Gene: 29221 Rat
- Omim: 608313 Human
- SwissProt: P05089 Human
- SwissProt: Q61176 Mouse
- SwissProt: P07824 Rat
- Unigene: 440934 Human
see all -
别名
- A I antibody
- Al antibody
- ARG 1 antibody
see all
图片
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All lanes : Anti-Liver Arginase antibody (ab92274) at 0.03 µg/ml
Lane 1 : pig liver tissue lysate
Lane 2 : mouse liver tissue lysate
Lane 3 : rat liver tissue lysate
Lysates/proteins at 35 µg per lane.
Predicted band size: 35 kDa
Observed band size: 35 kDa -
Anti-Liver Arginase antibody (ab92274) at 0.01 µg/ml + human liver lysate in RIPA buffer at 35 µg
Predicted band size: 35 kDa
数据表及文件
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Datasheet download
文献 (3)
ab92274 被引用在 3 文献中.
- Han GH et al. Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats. Cell Prolif 54:e13050 (2021). PubMed: 33960559
- Hashimoto T et al. Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. J Invest Dermatol 140:850-859.e3 (2020). PubMed: 31626785
- Kim SJ et al. Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury. Sci Rep 8:3176 (2018). PubMed: 29453346