Anti-LLGL2抗体(ab73304)
Key features and details
- Rabbit polyclonal to LLGL2
- Suitable for: ELISA, IHC, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-LLGL2抗体 -
描述
兔多克隆抗体to LLGL2 -
宿主
Rabbit -
特异性
Reacts specifically with human 113 kDa protein. -
经测试应用
适用于: ELISA, IHC, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide derived from N terminal domain of human LLGL2 protein
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73304于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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IHC |
1/100 - 1/1000.
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WB |
1/1000 - 1/5000. Predicted molecular weight: 113 kDa.
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说明 |
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ELISA
Use at an assay dependent concentration. |
IHC
1/100 - 1/1000. |
WB
1/1000 - 1/5000. Predicted molecular weight: 113 kDa. |
靶标
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功能
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity. -
序列相似性
Belongs to the WD repeat L(2)GL family.
Contains 14 WD repeats. -
翻译后修饰
Phosphorylated at Ser-653 by PRKCI. Phosphorylation is enhanced during cell polarization induced by calcium. Phosphorylation may occur during the cell-cell contact-induced cell polarization and may contribute to the segregation of LLGL2 from the PRKCI/aPKC and PARD6B/Par-6 complex. -
细胞定位
Cytoplasm. Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells. - Information by UniProt
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数据库链接
- Entrez Gene: 3993 Human
- Entrez Gene: 217325 Mouse
- Entrez Gene: 360661 Rat
- SwissProt: Q6P1M3 Human
- SwissProt: Q3TJ91 Mouse
- Unigene: 514477 Human
- Unigene: 290450 Mouse
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别名
- HGL antibody
- Human giant larvae homolog antibody
- L2GL2 antibody
see all
数据表及文件
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Datasheet download
文献 (1)
ab73304 被引用在 1 文献中.
- Xu Y et al. TGF-β3 induces lactate production in Sertoli cell through inhibiting the Notch pathway. Andrology 10:1644-1659 (2022). PubMed: 36057850