Anti-LATS1/WARTS ((phospho T1079) +LATS2 (phospho T1041)抗体(ab111344)
Key features and details
- Rabbit polyclonal to LATS1/WARTS (phospho T1079) + LATS2 (phospho T1041)
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-LATS1/WARTS ((phospho T1079) +LATS2 (phospho T1041)抗体 -
描述
兔多克隆抗体to LATS1/WARTS (phospho T1079) + LATS2 (phospho T1041) -
宿主
Rabbit -
经测试应用
适用于: IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse -
免疫原
This product was produced with the following immunogens:
Synthetic peptide corresponding to Human LATS1/WARTS (C terminal) (phospho T1079).
Synthetic peptide corresponding to Human LATS2 (phospho T1041). -
阳性对照
- Human brain tissue.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49.1% PBS, 0.88% Sodium chloride, 50% Glycerol
PBS (without Mg2+ and Ca2+) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
纯化说明
ab111344 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111344于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-P |
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
说明 |
---|
IHC-P
1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
靶标
-
细胞定位
LATS1/WARTS: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localizes to the centrosomes throughout interphase but migrates to the mitotic apparatus, including spindle pole bodies, mitotic spindle, and midbody, during mitosis. LATS2: Cytoplasm > cytoskeleton > centrosome. Cytoplasm. Cytoplasm > cytoskeleton > spindle pole. Co-localizes with STK6 at the centrosomes during interphase, early prophase and cytokinesis. Migrates to the spindle poles during mitosis, and to the midbody during cytokinesis. -
数据库链接
- Entrez Gene: 26524 Human
- Entrez Gene: 9113 Human
- Entrez Gene: 16798 Mouse
- Entrez Gene: 50523 Mouse
- Omim: 603473 Human
- Omim: 604861 Human
- SwissProt: O95835 Human
- SwissProt: Q9NRM7 Human
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (15)
ab111344 被引用在 15 文献中.
- Drexler R et al. The clinical relevance of the Hippo pathway in pancreatic ductal adenocarcinoma. J Cancer Res Clin Oncol 147:373-391 (2021). PubMed: 33098447
- Ji L et al. LncRNA AGAP2-AS1 Promotes Cancer Cell Proliferation, Migration and Invasion in Colon Cancer by Forming a Negative Feedback Loop with LINC-PINT. Cancer Manag Res 13:2153-2161 (2021). PubMed: 33688258
- Kuang MJ et al. Exosomal miR-365a-5p derived from HUC-MSCs regulates osteogenesis in GIONFH through the Hippo signaling pathway. Mol Ther Nucleic Acids 23:565-576 (2021). PubMed: 33510944
- Wang K et al. Long non-coding RNA ASAP1-IT1 suppresses ovarian cancer progression by regulating Hippo/YAP signaling. Int J Mol Med 47:N/A (2021). PubMed: 33576454
- Zhang Y et al. Inhibin βA is an independent prognostic factor that promotes invasion via Hippo signaling in non‑small cell lung cancer. Mol Med Rep 24:N/A (2021). PubMed: 34505633