Anti-KA1抗体(ab67404)
Key features and details
- Rabbit polyclonal to KA1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
概述
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产品名称
Anti-KA1抗体
参阅全部 KA1 一抗 -
描述
兔多克隆抗体to KA1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
A 14 amino acid peptide near the amino terminus of human KA1.
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阳性对照
- Rat brain lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67404于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 107 kDa).
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说明 |
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WB
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 107 kDa). |
靶标
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功能
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. -
序列相似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily. -
细胞定位
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 24406 Rat
- SwissProt: Q01812 Rat
- Unigene: 10049 Rat
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别名
- EAA 1 antibody
- EAA1 antibody
- Excitatory amino acid receptor 1 antibody
see all
图片
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Lane 1 : Anti-KA1 antibody (ab67404) at 0.5 µg/ml
Lane 2 : Anti-KA1 antibody (ab67404) at 1 µg/ml
Lane 3 : Anti-KA1 antibody (ab67404) at 2 µg/ml
All lanes : rat brain lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 107 kDa
Observed band size: <97 kDa why is the actual band size different from the predicted?
Additional bands at: 108 kDa. We are unsure as to the identity of these extra bands.
N.B. Despite its predicted molecular weight, KA1 often migrates at a lower molecular weight in SDS-PAGE.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab67404 被引用在 3 文献中.
- Ciarpella F et al. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. iScience 24:103438 (2021). PubMed: 34901791
- Gu L et al. Erythropoietin exerts a neuroprotective function against glutamate neurotoxicity in experimental diabetic retina. Invest Ophthalmol Vis Sci 55:8208-22 (2014). PubMed: 25335981
- Marrocco J et al. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. J Neurosci 32:17143-54 (2012). Rat . PubMed: 23197707