Anti-KA1抗体(ab67402)
Key features and details
- Rabbit polyclonal to KA1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-KA1抗体
参阅全部 KA1 一抗 -
描述
兔多克隆抗体to KA1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Rat -
免疫原
Synthetic peptide corresponding to Mouse KA1 aa 1-18 (C terminal). An 18 amino acid synthetic peptide near the carboxy terminus of the mouse Grik4.
(Peptide available asab209614) -
阳性对照
- Rat brain lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Allow to warm to room temp and agitate gently before aliquotting. Store at -20°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab67402于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (1) |
说明 |
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WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 108 kDa).
N.B. KA1 often migrates at a lower molecular weight in SDS-PAGE.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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功能
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. -
序列相似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily. -
细胞定位
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 24406 Rat
- SwissProt: Q01812 Rat
- Unigene: 10049 Rat
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别名
- EAA 1 antibody
- EAA1 antibody
- Excitatory amino acid receptor 1 antibody
see all
图片
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Lane 1 : Anti-KA1 antibody (ab67402) at 0.5 µg/ml
Lane 2 : Anti-KA1 antibody (ab67402) at 1 µg/ml
Lane 3 : Anti-KA1 antibody (ab67402) at 2 µg/ml
All lanes : Rat brain lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 108 kDa
Observed band size: <97 kDa why is the actual band size different from the predicted?
N.B. KA1 often migrates at a lower molecular weight in SDS-PAGE.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab67402 被引用在 1 文献中.
- Bonnet CS et al. AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI Insight 5:N/A (2020). PubMed: 32544091