JC-1,Mitochondrial膜potential dye (ab141387)
Key features and details
- Mitochondrial membrane-potential dye
- CAS Number: 3520-43-2
- Purity: > 95%
Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
JC-1,Mitochondrial膜potential dye -
描述
Mitochondrial膜-potential dye -
纯度
> 95% -
CAS编号
3520-43-2 -
化学结构
性能
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激发
519nm -
发射
590nm -
化学名称
5,6-Dichloro-2-[(E)-3-(5,6-dichloro-1,3-diethyl-1,3-dihydro-2H-benzimidazol-2-ylidene)-1-prop-1-enyl]-1,3-diethyl-1H-benzimidazolium iodide
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分子量
652.23 -
PubChem识别号
5492929 -
存放说明
Shipped at 4°C. Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解度概述
Soluble in DMSO to 25 mM
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处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCN1C2=CC(=C(C=C2[N+](=C1C=CC=C3N(C4=CC(=C(C=C4N3CC)Cl)Cl)CC)CC)Cl)Cl.[I-] -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (19)
ab141387 被引用在 19 文献中.
- Ding J et al. HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway. Mol Biol Rep 50:961-970 (2023). PubMed: 36376538
- Wang D et al. SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1. Cell Death Differ 30:369-382 (2023). PubMed: 36443440
- Chen F et al. Monitoring Mitochondria Function in Ferroptosis. Methods Mol Biol 2712:103-115 (2023). PubMed: 37578700
- Dong X et al. Inhibition of miR-421 Preserves Mitochondrial Function and Protects against Parkinson's Disease Pathogenesis via Pink1/Parkin-Dependent Mitophagy. Dis Markers 2022:5186252 (2022). PubMed: 35664430
- Rodríguez-Nuevo A et al. Oocytes maintain ROS-free mitochondrial metabolism by suppressing complex I. Nature 607:756-761 (2022). PubMed: 35859172