Anti-IL-34抗体(ab111978)
Key features and details
- Rabbit polyclonal to IL-34
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-IL-34抗体
参阅全部 IL-34 一抗 -
描述
兔多克隆抗体to IL-34 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant full length protein corresponding to Human IL-34 aa 21-242. (BC029804)
-
阳性对照
- Human fetal spleen tissue; Human fetal brain lysate.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111978于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 27 kDa).
|
说明 |
---|
WB
1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 27 kDa). |
靶标
-
功能
Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R. -
组织特异性
Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. -
序列相似性
Belongs to the IL-34 family. -
细胞定位
Secreted. - Information by UniProt
-
数据库链接
- Entrez Gene: 146433 Human
- Entrez Gene: 76527 Mouse
- Entrez Gene: 498951 Rat
- Omim: 612081 Human
- SwissProt: Q6ZMJ4 Human
- SwissProt: Q8R1R4 Mouse
- SwissProt: Q4KM46 Rat
- Unigene: 461214 Human
see all -
别名
- C16orf77 antibody
- Chromosome 16 open reading frame 77 antibody
- FPT025 antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab111978 被引用在 1 文献中.
- Ciccia F et al. IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14brightCD16+ monocytes. Rheumatology (Oxford) 52:1009-17 (2013). IHC-P ; Human . PubMed: 23392590