Anti-Inhibin beta A抗体(ab97705)
Key features and details
- Rabbit polyclonal to Inhibin beta A
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Inhibin beta A抗体
参阅全部 Inhibin beta A 一抗 -
描述
兔多克隆抗体to Inhibin beta A -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide, corresponding to a sequence within amino acids 362-423 (SGSSLSFHST VINHYRMRGH SPFANLKSCC VPTKLRPMSM LYYDDGQNII KKDIQNMIVE EC) of Human Inhibin beta A (NP_002183).
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阳性对照
- H1299, HeLa S3 and HepG2 whole cell lysate (ab7900); HeLa cells; 293T, A431, MOLT4 and Raji cell lines.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab97705于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 47 kDa.
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ICC/IF |
1/100 - 1/200.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 47 kDa. |
ICC/IF
1/100 - 1/200. |
靶标
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功能
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. -
序列相似性
Belongs to the TGF-beta family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 3624 Human
- Omim: 147290 Human
- SwissProt: P08476 Human
- Unigene: 583348 Human
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别名
- Activin beta-A chain antibody
- EDF antibody
- Erythroid differentiation factor antibody
see all
图片
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All lanes : Anti-Inhibin beta A antibody (ab97705) at 1/1000 dilution
Lane 1 : H1299 whole cell lysate
Lane 2 : HeLa S3 whole cell lysate
Lane 3 : HepG2 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 47 kDa
10% SDS-PAGE. -
ab97705, at 1/200 dilution, staining Inhibin beta A in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (8)
ab97705 被引用在 8 文献中.
- Zhang Y et al. Inhibin βA is an independent prognostic factor that promotes invasion via Hippo signaling in non‑small cell lung cancer. Mol Med Rep 24:N/A (2021). PubMed: 34505633
- Qiu F et al. Development and Verification of an Immune-Based Gene Signature for Risk Stratification and Immunotherapeutic Efficacy Assessment in Gastric Cancer. Dis Markers 2021:4251763 (2021). PubMed: 34804261
- Fuentelsaz-Romero S et al. GM-CSF Expression and Macrophage Polarization in Joints of Undifferentiated Arthritis Patients Evolving to Rheumatoid Arthritis or Psoriatic Arthritis. Front Immunol 11:613975 (2020). PubMed: 33679701
- Iriuchishima H et al. Activin A: a novel urinary biomarker of renal impairment in multiple myeloma. Biosci Rep 39:N/A (2019). PubMed: 31072919
- Takei Y et al. Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis. PLoS One 14:e0223703 (2019). PubMed: 31613925
- Hosen MR et al. Airn Regulates Igf2bp2 Translation in Cardiomyocytes. Circ Res 122:1347-1353 (2018). PubMed: 29483092
- Shih B et al. Identification of biomarkers in sequential biopsies of patients with chronic wounds receiving simultaneous acute wounds: a genetic, histological, and noninvasive imaging study. Wound Repair Regen 20:757-69 (2012). PubMed: 22985042
- Arai KY et al. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology 152:3779-90 (2011). WB ; Human . PubMed: 21828177