Anti-ITIH2/SHAP抗体(ab118257)
Key features and details
- Rabbit polyclonal to ITIH2/SHAP
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-ITIH2/SHAP抗体
参阅全部 ITIH2/SHAP 一抗 -
描述
兔多克隆抗体to ITIH2/SHAP -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Recombinant fragment corresponding to Human ITIH2/SHAP aa 124-321.
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阳性对照
- WB: Fetal brain lysate IHC-P: Fetal brain tissue
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab118257于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa).
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IHC-P |
1/100 - 1/500.
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa). |
IHC-P
1/100 - 1/500. |
靶标
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功能
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes. -
组织特异性
Plasma. -
序列相似性
Belongs to the ITIH family.
Contains 1 VIT domain.
Contains 1 VWFA domain. -
翻译后修饰
Heavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
Phosphorylation sites are present in the extracelllular medium. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 3698 Human
- Entrez Gene: 16425 Mouse
- Omim: 146640 Human
- SwissProt: P19823 Human
- SwissProt: Q61703 Mouse
- Unigene: 75285 Human
- Unigene: 182043 Mouse
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别名
- AI747202 antibody
- H2P antibody
- IGHEP2 antibody
see all
图片
数据表及文件
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Datasheet download
文献 (3)
ab118257 被引用在 3 文献中.
- Heindel DW et al. Glycomic Analysis Reveals a Conserved Response to Bacterial Sepsis Induced by Different Bacterial Pathogens. ACS Infect Dis 8:1075-1085 (2022). PubMed: 35486714
- Martin J et al. Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-a-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation. J Biol Chem 291:13789-801 (2016). PubMed: 27143355
- He H et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . PubMed: 23878196